Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that the Y has little biological importance beyond sex determination.

The Y chromosome is among the smallest in the human body and carries the fewest genes. Researchers are paying renewed attention to its role in cancer—specifically, what happens when it vanishes.

Three specific genes on chromosome 21 drive widespread brain changes in Down syndrome, uncovering a new framework for ...

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least in lab-grown human cells. The project, led by Dr. Ryotaro Hashizume of Mie ...

Conservation of genomic sequences between species indicates regions of functional importance, containing protein-coding gene, non-coding genes or regulatory elements. In the December 5 Nature, ...

Each known chromosome 21 gene and predicted open reading frame (ORF), identified using MWG-Biotech's non-redundant proprietary database, is represented once in the array by a 40-nucleotide-long ...

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs). What is ...

How does the CRISPR Down Syndrome breakthrough work to remove the extra chromosome 21? We are closer than ever to a world where a genetic condition affecting one in every 700 babies could be addressed ...

Sex chromosomes are chromosomes, or packages of DNA, that are found inside the nucleus of all of your cells. There are two different kinds: X and Y, which determine whether you’re biologically male ...