Cytokinesis is the physical separation of two cells that occurs after the completion of mitosis. The mechanism underlying it is very complex. Until recently, the processes that lead to cleavage furrow ...
Polarization of a cell refers to the loss of symmetry that most cells undergo in response to external or internal signals. Some of the mechanisms for initiating and transducing polarity are shared by ...
Inhibition of cytokinesis by overexpression of NudCL that is localized to the centrosome and midbody
Because of the downregulation of dynein intermediate chain (IC) in cells depleted of NudCL, we tried to determine the protein levels of dynein IC in cells with NudCL overexpression. The result ...
Treatment options for congenital heart disease are limited by the relative inability of mature cardiac muscle cells (cardiomyocytes) to generate new cardiomyocytes through proliferation after birth.
How does the cell organize multi-step cytokinetic processes to successfully separate cells after division? The final step in cell division is cytokinesis, where the cytoplasm divides into two after ...
As cell biologists, Université de Montréal professor Greg FitzHarris and his Ph.D. student Lia Paim are very interested in fertility and what happens inside the eggs and embryos of the mice they study ...
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